| Noel Neill | Lois Lane |
| Tommy Bond | Jimmy Olsen |
| Jack Ingram | Anton |
| Charles Quigley | Dr. Hackett [Chs. 6-15] |
| George Meeker | Driller |
| Rusty Wescoatt | Elton [Chs. 7-15] |
| Stephen Carr | Morgan [Chs. 3-4] |
| Emmett Vogan | Secretary of National Security [Chs. 3, 8] |
| Luana Walters | Lara, mother of Superman [Ch. 1] |
| Ed Cassidy | Eben Kent [Ch. 1] |
| Fred Aldrich | Policeman at Museum - Ch. 5 |
| Phil Arnold | Taxi Driver [Ch. 2] |
| Jack Chefe | Dupe [Ch. 14] |
| Alan Dinehart III | Clark as a small boy [Ch. 1] |
| William Fawcett | Phoney News-Hawker [Ch. 7] |
| Jack George | Railroad Workman [Ch. 1] |
| Ralph Hodges | Teenage Clark Kent [Ch. 1] |
| I. Stanford Jolley | Sheriff [Chs. 11-12] |
| Knox Manning | Narrator |
| Frank O'Connor | Spectator at fire [Ch.2]/Police Chief Forman [Ch. 15] |
| Leonard Penn | Electronics Store Owner/Henchman [Ch. 14] |
| Gene Roth | Carson the Conductor [Ch. 2] |
| Charles Sherlock | Daily Planet Worker [Ch. 11 & 13] |
| Bert Stevens | Man Sent for Help at RR Station - Ch. 1 |
| Peggy Wynne | Gloria the Switchboard-Receptionist - Chs. 2, 3, 11 |
| Carol Forman | 'Spider Lady' |
| Pierre Watkin | Perry White |
| Terry Frost | Brock |
| Charles King | Conrad [Chs. 6-15] |
| Herbert Rawlinson | Dr. Arnold Graham [Chs. 3, 9-10, 15] |
| Forrest Taylor | Prof. Arnold Leeds [Chs. 3-4] |
| Frank Lackteen | Hawkins, the stoolie [Chs. 4-7] |
| Nelson Leigh | Jor-El, father of Superman [Ch. 1] |
| Robert Barron | Ro-Zon, leader of Krypton [Ch. 1] |
| Virginia Carroll | Martha Kent [Ch. 1] |
| Kirk Alyn | Superman/Clark Kent |
| Jimmy Aubrey | Wave Tracer |
| Edmund Cobb | Auto Mechanic [Ch. 10] |
| Frank Ellis | Mine Security Guard [Ch. 2] |
| Eddie Foster | Fred Collier, Mining Engineer [Ch. 12] |
| Frank Hagney | Henchman [Ch. 3] |
| Reed Howes | Henchman Jackson [Ch. 8] |
| Tom London | Old Timer at Mine [Ch. 2] |
| Wheeler Oakman | Dr. Fredrick Larkin - Ch. 11 |
| Eddie Parker | Truck Driver [Chs. 11-12] |
| Stanley Price | Crandall the Thug [Ch. 3] |
| Charles Schaeffer | Thug Holding Lois |
| Paul Stader | Henchman Irwin [Ch. 8] |
| Al Wyatt Sr | .Thug Holding Lois |
